Nanodrop™ ExtY

Utilizing the Nanodrop series fluidics module, the Nanodrop ExtY is a compact solution for low volume, high-precision pipetting that allows two sets of 4 tips each to dispense reagent to all wells of a standard SBS plate, facilitating rapid dispense of two reagents. Additionally, 4 tips can access any well position, enabling crystallization screens. The Nanodrop ExtY aspirates and dispenses a broad range of liquids including DMSO and features the Nanobuilder© software system that enables a wide range of applications and data manipulation. Innovadyne’s patented technology isolates the solenoid dispense actuators from the sample path. This assures long life and easy, low-cost maintenance.

Videos

Features

Non-contact and contact dispense
Exceptional dynamic range (nanoliter to milliliter)
Aspirate and dispense with individual channel articulation
Single tip addition for expensive reagents
Simple fluid path with no moving parts
FEP, SS, sapphire wetted parts compatible with commonly used solvents
96-, 384-, and 1536-well plate formats
Crystal plates supported
Easy to program, easy to automate
Simple cleaning and maintenance

Applications

Protein Crystallography

Coarse and fine screen creation
Mother liquor transfer
Protein additions
Hanging and sitting drop

HTS

Sample transfer
Reagent addition

PCR

Template transfers
Cocktail addition
Sequencing

Performance Specifications

Plate Formats	96, 384, 1536, 1536 standard, low profile, deep well and crystallography plates
Plate Positions	1
Return to Spot Accuracy	0.1 mm
Dispense Functions	1, 4, 8-tip bulk reagent additions to all positions
Aspirate Modes	All the same volumes, independent
Dispense Modes	All the same volumes, independent
Aspiration Range	0.1 - 500 µL
Dispensing Range	0.1 - 40 µL (non-contact) 25 - 500 µL (contact)
Dispensing Precision	CV ≤ 10% at 100 nL CV ≤ 7% at 200 nL CV ≤ 5% at 1 µL
Dispensing Accuracy	±10% at 100 nL ±7% at 200 nL ±5% at 1 µL
Dead Volume	1.44 µL/channel at 1 µL across 384-well plate
Syringe Capacity	500, 1000 µL
Cycle Time	20s/transfer <60s 1 µL reagent addition (single tip/96-well plate) <17 s 1 µL reagent addition (8-tips/1536-well plate)

Technical Specifications

Dimension	Fluidics Module	Stage Module
Height	33.0 cm (13 in)	33.0 cm (13 in)
Width	27.9 cm (11 in)	24.1 cm (9.5 in)
Depth	44.5 cm (18 in)	37.5 cm (14.75 in)
Weight	11.3 kg (25 lb)	11.3 kg (25 lb)

Environmental	10 to 40°C, 80% RH
System Gas	Standard grade helium (99.7% pure)
Dispense Tips	304 SS, sapphire
Reagent Trays	Two 10 mL units, disposable
Interface	RS-232, Nanodrop GUI software